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Kidney disease symptoms often develop slowly and may go unnoticed in the early stages. Common symptoms include frequent urination, especially at night, swelling in the feet, ankles, hands, or face due to fluid retention, and persistent fatigue or weakness. People may also experience loss of appetite, nausea, vomiting, or unexplained weight changes. Changes in urine color, foamy urine, or blood in the urine can be warning signs of kidney problems. Other kidney disease symptoms include difficulty concentrating, muscle cramps, dry or itchy skin, and high blood pressure. Early recognition of kidney disease symptoms helps in timely diagnosis and effective treatment.