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Potassium channels, one of the most prevalent kinds of ion channel, are present in almost every creature. Potassium channels exist in nearly all the cell types and regulate wide cell processes. Creative Biolabs, experts in ion channel screening field, offers reliable potassium channel screening service for worldwide scientists to ease their research. Learn more: Potassium Channel Screening Service

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ADCs Cytotoxin with Linkers
The efficacy of ADCs significantly depends on the choice of cytotoxins and linkers. Commonly used cytotoxins include microtubule inhibitors like maytansinoids and auristatins, which require effective linkers for successful conjugation. The design of these linkers affects the overall therapeutic window of ADCs. For instance, cleavable linkers can provide an efficient release of the cytotoxin within the target cells, allowing for a potent anticancer effect, while providing reduced toxicity to normal cells.